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KMID : 0616120080390020091
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Korean Journal of Pharmacognosy
2008 Volume.39 No. 2 p.91 ~ p.94
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Phytochemical Constituents from the Aerial Parts of Paris verticillata
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Lee Kyu-Ha
Lee Kang-Ro
Choi Sang-Un
Lee Il-Kyun
Kim Ki-Hyun
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Abstract
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Column chromatographic separation of the MeOH extract from the aerial parts of Paris verticillata led to the isolation of three phenolics, two terpene glucosides and two pyrrolidine alkaloids. Their structures were characterized to be methyl caffeate (1), 5-hydroxy pyrrolidin-2-one (2), vanillic acid (3), benzyl alcohol glucopyranoside (4), (6S, 9R)-roseoside (5), staphylionoside H (6) and 5-methoxy pyrrolidin-2-one (7) by spectroscopic means. The isolated compounds (1-7) were for the first time reported from this source. The isolated compounds were tested for their cytotoxicity against four human tumor cell lines by SRB method in vitro.
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KEYWORD
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Liliaceae, Paris verticillata, Pyrrolidine alkaloid, phenolic comopound
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